NAD+ 500 mg
Cellular fuel
Nicotinamide Adenine Dinucleotide — the coenzyme that runs mitochondria, sirtuin activation, and DNA repair. Levels naturally decline ~50% by age 50.
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RxPrescription Included
NAD+ Boost Spray
A prescription nasal spray for cellular energy, mental clarity, faster recovery, and longevity support.
$129/ 30-day supply (30 ml, 500 mg)
NAD+ powers every cellular process that gives you energy, focus, and recovery. Levels drop ~50% by age 50 — direct nasal delivery replenishes them fast.
Important Safety Information⚕️
Consultation Included
This is a prescription-strength product. Your order includes a free medical consultation with one of our licensed providers.
How it works:
- • Complete your online health intake after checkout.
- • A provider will review your information within 24-48 hours.
- • If approved, your prescription is sent to our pharmacy for discreet shipping.
If our providers determine this treatment isn't appropriate for you, your card authorization is released — you're never charged.
🔒 HIPAA Secure
🧪 Compounded in USA
📋 No Charge until approved
Cellular Energy✦Mental Clarity✦Faster Recovery✦Longevity Support✦Cellular Energy✦Mental Clarity✦Faster Recovery✦Longevity Support✦Cellular Energy✦Mental Clarity✦Faster Recovery✦Longevity Support✦
Cellular Energy✦Mental Clarity✦Faster Recovery✦Longevity Support✦Cellular Energy✦Mental Clarity✦Faster Recovery✦Longevity Support✦Cellular Energy✦Mental Clarity✦Faster Recovery✦Longevity Support✦
Proven Ingredients
Why our formula works
One molecule. Direct nasal delivery. Compounded by a U.S. licensed pharmacy and reviewed by a board-certified physician before every prescription.
Nasal delivery
Fast absorption
Bypasses first-pass liver metabolism that limits oral NAD+ supplements. Direct mucosal uptake reaches systemic circulation in minutes.
Provider supervised
Dr. Ressalam reviews
Every prescription reviewed individually — including screening for active cancer, mood disorders, and current medications that interact with NAD+ pathways.
“
Mitochondria don't run on willpower. They run on NAD+. Replenishing it directly is the fastest way to feel the difference.
Dr. Annie Ressalam, MD
Internist · Medical Director, HerTeleMeds
The science
How NAD+ powers your cells
NAD+ is the coenzyme that runs the energy machinery in every cell. Three things happen when levels are restored.
↓ 50%
Natural decline
NAD+ levels drop roughly 50% between age 25 and age 50 — even in healthy adults. Direct supplementation reverses the trend.
ATP
Mitochondrial energy
NAD+ is essential for ATP production — the energy currency of every cell. Restoring it lifts physical and cognitive stamina.
Sirtuins
DNA repair
NAD+ activates sirtuins and PARP enzymes that repair DNA damage and regulate longevity pathways.
Trusted by thousands
Real women seeing real results
Two weeks in and the brain fog I'd been blaming on age was gone. I forgot what real focus felt like.
— HTM Patient, MD
My skin felt like a stranger's after menopause. NAD+ Boost Spray brought it back home.
— HTM Patient, VA
I tried oral NAD+ for years and felt nothing. The nasal spray is a different category — I feel it.
— HTM Patient, GA
Personalize your treatment
Top 3 concerns by age
Hair thinning has different drivers at different life stages. Here's how HairMax addresses the most common concerns at each.
Workout recovery
Slower bounce-back from training. NAD+ supports mitochondrial repair so muscles recover overnight instead of in days.
Afternoon fatigue
The 3 PM crash that wasn't there at 25. Restoring cellular NAD+ levels lifts sustained energy without caffeine spikes.
Mental sharpness
Subtle declines in focus during long work blocks. NAD+ powers neuronal mitochondria; restoring it sharpens cognitive endurance.
The mechanism
Three pillars of restored NAD+
Energy, repair, and longevity all converge on one molecule. Restoring it does three things at once.
I
Power mitochondria
NAD+ is the coenzyme that powers ATP production — the energy currency of every cell. Restoring it lifts cellular stamina from the inside.
II
Activate DNA repair
NAD+ activates sirtuins and PARP enzymes that fix DNA damage from UV, oxidative stress, and aging. More NAD+, more repair.
III
Support longevity pathways
Sirtuins, regulated by NAD+, control gene expression linked to healthspan. Sustained NAD+ levels keep these pathways active.
Eligibility
Is NAD+ Boost Spray right for you?
NAD+ is well-tolerated by most adults — but a few specific medical situations require a conversation with your provider before starting.
Good fit if you are
- ✓Healthy adults seeking improved energy, focus, recovery, or longevity support.
- ✓Familiar with the underlying biology and committed to consistent daily use over weeks to feel the cumulative effect.
- ✓Comfortable with a nasal-delivery prescription used daily under physician supervision.
Talk to your provider before starting if
- !You currently have an active cancer diagnosis or are undergoing chemotherapy.
- !You are pregnant, breastfeeding, or trying to conceive (limited safety data for NAD+ in these populations).
- !You have a personal or family history of bipolar disorder or psychiatric mood activation.
- !You have severe nasal allergies, chronic sinusitis, or recent nasal surgery.
Dr. Ressalam reviews these factors during the intake. If NAD+ Boost Spray isn't the right fit, your card authorization is released and you are never charged.
Pricing
Compare to traditional treatment
NAD+ Boost Spray bundles a 500 mg compounded NAD+ nasal formulation, a physician visit, and discreet shipping into one monthly cost — a fraction of the price of IV NAD+ therapy.
NAD+ Boost Spray
Traditional regimen
Monthly cost
$129 / mo
$600–$1,500+ for IV NAD+
Dermatologist visit
Included
$150–$300 separate
Treatment route
Nasal spray
IV infusion (clinic visit, ~3 hrs)
Shipping
Free, discreet
Pharmacy pickup
Provider follow-up
Anytime
Per appointment
Traditional NAD+ regimen estimate based on per-session IV NAD+ infusion pricing at functional medicine clinics in 2026, typically requiring 6–10 sessions for comparable cumulative dose.
How it works
Get started without a visit
Skip the waiting room. Tell us about your health history and goals, get evaluated by Dr. Ressalam, and — if appropriate — your nasal spray ships discreetly.
- 1Answer a few questions about your health
- 2Dr. Ressalam reviews your submission
- 3Get approved (usually within 24 hours)
- 4Your prescription ships straight to you
- 5Stay supported with clinician guidance anytime
Application protocol
How to use NAD+ Boost Spray
Nasal absorption is fast — most patients feel a subtle lift within 15–30 minutes of dosing. Use as your provider directs; the standard protocol below applies to most prescriptions.
- 01
Prime the bottle
Before first use, prime by pumping into the air 4–6 times until a fine mist appears. Repeat priming if you haven't used the spray in 24+ hours.
- 02
Tilt head slightly forward
Slight forward tilt — not back. This positions the nasal cavity for optimal absorption and avoids the spray running down your throat.
- 03
Spray into one nostril
Insert the nozzle into one nostril, close the other with a finger, and spray once while inhaling gently through that nostril.
- 04
Repeat in the other nostril
Switch nostrils and repeat. Most prescriptions call for 1 spray per nostril, once or twice daily — follow your provider's instructions.
- 05
Hold and breathe normally
Avoid blowing your nose for 5–10 minutes after dosing to allow full mucosal absorption. Resume normal activity.
When to apply
Most patients dose in the morning for sustained-energy effect. Avoid late-evening dosing — NAD+ can be subtly stimulating for some people.
Mild tingling normal
A brief warm or tingling sensation in the nostril after dosing is normal. Persistent burning or pain means stop and contact your provider.
Cumulative effect
Acute lift within 30 minutes; full benefits compound over 4–8 weeks of consistent daily use as cellular NAD+ pools refill.
Storage
Refrigerate the bottle between uses. NAD+ is unstable at room temperature for extended periods. Discard 30 days after first use.
What to expect
Your results timeline
Day 1
Acute lift
Most patients feel subtle energy and mental clarity within 30 minutes of the first dose. Confirms absorption is working.
Wk 1–2
Cellular pools refill
NAD+ pools rebuild across tissues. Sustained energy throughout the day; afternoon crashes diminish.
Wk 3–6
Recovery accelerates
Workout recovery, sleep quality, and stress resilience all noticeably improve as mitochondrial efficiency lifts.
Wk 6–12
Cognitive benefits
Word recall, focus, and decision speed improve. Sirtuin-driven DNA repair accumulates measurable benefits.
Wk 12+
Steady state
Maintenance phase. Most patients continue daily dosing — NAD+ benefits last only as long as levels stay restored.
Timing reflects average response from clinical literature on intranasal NAD+ supplementation. Individual results vary based on baseline NAD+ levels, age, and consistency of use.
Your questions
Frequently asked
Is intranasal NAD+ better than oral or IV?
+
Oral NAD+ is largely destroyed by stomach acid and first-pass liver metabolism — most never reaches your cells. IV NAD+ works but requires 2–3 hour clinic visits at $200–400 per session. Nasal delivery hits the bloodstream directly through the mucosa within minutes, at a fraction of the cost.
How fast will I notice a difference?
+
Most patients feel a subtle lift in energy or mental clarity within 30 minutes of the first dose. Cumulative benefits — better recovery, sustained focus, deeper sleep — build over 4–8 weeks of daily use.
Is it safe to use long-term?
+
NAD+ is a naturally-occurring molecule produced in every cell. Daily intranasal supplementation is well-tolerated for long-term use in healthy adults under provider supervision. Dr. Ressalam reviews ongoing use at follow-up.
Can I use this if I have an active cancer diagnosis?
+
No. NAD+ supports cellular metabolism broadly, including in pathways that some cancers exploit. We do not prescribe NAD+ during active cancer treatment. Tell Dr. Ressalam during the intake.
Will this affect my mood?
+
Most patients feel calmly energized, similar to a clean caffeine effect without the jitters. A small subset with bipolar disorder or hypomanic tendencies can experience mood activation — please disclose any psychiatric history during intake.
How does this compare to NMN or NR supplements?
+
NMN and NR are NAD+ precursors — your body has to convert them, which is inefficient and limits the dose that actually becomes NAD+. Direct NAD+ skips that conversion and delivers the active molecule itself.
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Formulas designed for you
Important Safety Information
- • For intranasal use only. Valid prescription required.
- • Contraindicated for patients with active cancer or undergoing chemotherapy.
- • Not for use during pregnancy, breastfeeding, or while trying to conceive (limited safety data).
- • Disclose any history of bipolar disorder or psychiatric mood activation before starting — NAD+ may produce subtle mood elevation.
- • Avoid use with severe nasal allergies, chronic sinusitis, or recent nasal surgery.
- • Refrigerate between uses; discard 30 days after first dose.
- • Discontinue and contact your provider if persistent nasal burning, headache, or unusual systemic symptoms occur.
Report negative side effects of prescription drugs to the FDA at www.fda.gov/medwatch or 1-800-FDA-1088.